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Jan 18, · 3rd Edition Intermediate Bill Mascull • • • • • •. _ PEARSON- - - - ' Longman FT FINANCIAL TIMES Scanned for Agus Suwanto- - - Pearson Education Limited. type: functional ( beta selection) functional ( positive selection) autoreactive ( negative selection) location: cortex: cortex: cortex/ medulla In order to pass the β- selection checkpoint, the β chain of the T cell receptor rearranged by the thymocyte must retain the structural properties allowing it to be presented on the surface of the thymocyte with pre- TCRα.
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